Tissue Repair & Regeneration Research//Research Reference

Wolverine (BPC-157 + TB-500)

Peptide-blend reference of BPC-157 and TB-500; evidence exists for the components separately, not for the combination.

Composition

Composition pending verification

Technical Dossier

Batch / Lot Number

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Testing Status

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Testing Laboratory

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Test Date

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Classification

Peptide blend: BPC-157 (pentadecapeptide) + TB-500 (thymosin beta-4 fragment)

Mechanism / Biological Target

BPC-157 is reported to promote angiogenesis and healing in animal injury models; TB-500 (thymosin beta-4 fragment) is reported to bind actin and support cell migration. Mechanisms are studied individually; combination synergy is not established.

Research Areas

Tissue RepairWound Healing

Research Overview

This entry is a combination/blend reference (commonly called 'Wolverine') describing two compounds: BPC-157 (a stable gastric pentadecapeptide) and TB-500 (a synthetic fragment of thymosin beta-4). Each component has supporting animal/in-vitro evidence for tissue repair, but robust clinical evidence specifically for this combination is lacking; the blend itself does not have clinical evidence. No combination efficacy is claimed. Not an approved drug.

Laboratory Storage & Handling

For laboratory/research material only. Store lyophilized material desiccated at -20°C, protected from light and moisture. Avoid repeated freeze-thaw cycles. Handle using appropriate laboratory PPE and follow institutional SOPs. Not for human administration, reconstitution for human use, or diagnostic use.

References

Stable Gastric Pentadecapeptide BPC 157: cytoprotection, organoprotection, and wound healing (review)
Sikiric P, et al. Curr Pharm Des (review), 2020.
Thymosin Beta-4 and TB-500 in Tissue Healing, Regeneration, and Musculoskeletal Repair: A Scoping Review
Applied Sciences (scoping review), 2024.

Available Documentation

Certificate of AnalysisPending / Not yet available

For Research Use Only

Compounds referenced on Peptide Underground are intended for laboratory and research purposes only. They are not intended to diagnose, treat, cure, or prevent any disease and are not intended for human consumption.