Neuroscience & Cognition Research//Research Reference
Selank
Synthetic tuftsin-analog heptapeptide investigated for anxiolytic and nootropic effects.
Technical Dossier
Batch / Lot Number
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Testing Status
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Testing Laboratory
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Test Date
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Classification
Synthetic heptapeptide; tuftsin analog (Thr-Lys-Pro-Arg-Pro-Gly-Pro)
Mechanism / Biological Target
Reported to act as a positive allosteric modulator of GABA receptors and to enhance benzodiazepine anxiolysis in animal models; the mechanisms are not fully characterized.
Research Areas
AnxietyCognitionNeuropeptide Research
Research Overview
Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro) is a synthetic heptapeptide structurally related to tuftsin, developed in Russia. Animal studies and Russian-language clinical reports describe anxiolytic and cognitive effects, and it has been used clinically in Russia for anxiety. Independent large-scale human efficacy data are limited and Selank is not FDA-approved.
Laboratory Storage & Handling
For laboratory/research material only. Store lyophilized material desiccated at -20°C, protected from light and moisture. Avoid repeated freeze-thaw cycles. Handle using appropriate laboratory PPE and follow institutional SOPs. Not for human administration, reconstitution for human use, or diagnostic use.
References
- Peptide Selank Enhances the Effect of Diazepam in Reducing Anxiety in Unpredictable Chronic Mild Stress Conditions in Rats
Kasian A, et al. 2017.
- The Molecular Aspects of Heptapeptide Selank Biological Activity
GABA receptor allosteric modulation study, 2018.
- Efficacy and possible mechanisms of action of a new peptide anxiolytic selank
Zozulia AA, et al. 2008.
Available Documentation
- Certificate of AnalysisPending / Not yet available
For Research Use Only
Compounds referenced on Peptide Underground are intended for laboratory and research purposes only. They are not intended to diagnose, treat, cure, or prevent any disease and are not intended for human consumption.